Oncology / MTP
Target identification, resistance analysis, and drug prioritization for oncology molecular target programs.
Decision Problems We Address
Oncology MTP teams face complex decisions that require integrating diverse data types
Target Identification
Which molecular targets are most relevant for a given tumor type based on genomic and pathway data?
Resistance Analysis
What resistance mechanisms might emerge, and how can compounds be designed to address them?
Drug Prioritization
Which compounds should advance based on target engagement, selectivity, and safety profiles?
Example Workflow
A typical oncology target identification workflow in MedChem
Tumor Genomics Input
Import genomic data, mutation profiles, and expression data for analysis.
Pathway Analysis
Map mutations to pathways and identify druggable nodes in the network.
Target Scoring
Score and rank potential targets based on multiple criteria.
Risk Assessment
Flag resistance mechanisms and off-target concerns.
Typical Outputs
MedChem workflows produce comprehensive decision documentation including:
- Ranked target list with supporting evidence
- Pathway dependency analysis
- Resistance mechanism predictions
- Compound-target interaction scores
- Safety and selectivity assessments
- Decision rationale documentation
Limitations
Important to understand what MedChem does not claim:
- Does not guarantee clinical efficacy
- Requires human expert review of all outputs
- Based on available data and known biology
- Not a substitute for experimental validation
Explore Oncology Solutions
See how MedChem can support your molecular target program decisions.